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Smoking Appears to Work Against HIV Drugs

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At a glance:

A new study of HIV-positive women finds that those who smoke cigarettes are more likely to have their disease progress to AIDS or to die. This, despite treatment with powerful HIV drugs known as antiretroviral therapy. 
 
A previous study of HIV-positive men found the same. 
 
The smoking women were more likely to come down with pneumonia and to be infected with HPV which leads to cervical cancer. 
 
While other factors may be at play, it can't be bad advice for HIV-positive patients to quit smoking.

Cigarette smoking may undermine benefits of potent antiretroviral ...

Aidsmap - 6/25/2006 8:05 PM

Cigarette smokers are more likely to be diagnosed with an AIDS-defining condition or to die, negating some of the benefits of potent antiretroviral therapy, according to a large prospective observational study of HIV-positive women from the United States. The study, published in the June issue of the American Journal of Public Health, is the first to find a relationship between smoking and HIV disease progression in women.
 
Until recently, there had been no studies on the effects of cigarette smoking in the era of potent antiretroviral therapy. Data from Galia and colleagues from the gay men's Multicenter AIDS Cohort Study had previously found no association between smoking and the risk of developing AIDS or dying, but since this was conducted prior to the availability of potent anti-HIV therapy, it was possible that the effects of smoking were masked by HIV's virulence.
 
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