COX-2 / Arthritis News

Allergy to NSAID Drugs May Extend to Tylenol-Type Medicines

At a glance:

Doctors and parents should be aware that children who are allergic to NSAID drugs such as ibuprofen may also have reactions to acetaminophen (Tylenol).  
 
This is known to occur in adults but has not been studied in children until now. 
 
Cox-2 inhibitors are also likely to pose a problem with these children.  
 
Pain and fever reduction are likely to be a challenge in these cases.


Acetaminophen Cross-Sensitivity Possible in Children Who React to ...

DG News - 6/13/2006 6:07 PM

VIENNA, AUSTRIA -- June 13, 2006 -- Children who are allergic to most nonsteroidal anti-inflammatory drugs (NSAIDs) may also be hypersensitive to acetaminophen, according to a study presented at the 25th Congress of the European Academy of Allergology and Clinical Immunology (EAACI).
 
The incidence of cross-reactive hypersensitivity to acetaminophen (paracetamol) among adolescents and adults with NSAID sensitivity is 7%, but its incidence in children is unknown. A better idea of its occurrence in children would be helpful, as these patients pose a significant treatment challenge, according to a study presented in a poster session on June 11th

 
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