Stroke News

Cardiac Drug May Work on Strokes, Too

At a glance:

A drug type currently used to treat heart disease may also be useful for early treatment of stroke victims, according to Duke University researchers. 
 
Cardiac glycosides increase calcium levels in cells, which guards against cell death. Stroke and heart disease can alter cell calcium concentration. 
 
While the research has not yet even been tested on live animals, it also is significant because of its method, which allows testing of a wide variety of drugs on a wide variety of cell functions. 
 


Study Spots Potential Stroke Drugs

eMaxHealth.com - 6/19/2006 7:12 PM

Using a novel screening technology, Duke University Medical Center researchers have shown that drugs called cardiac glycosides can protect brain cells from death after stroke in laboratory models, and that the drugs are effective even if delivered six hours or more after the onset of stroke conditions.
 
"This discovery is exciting because it may lead to interventions to prevent or lessen the amount of brain damage suffered after stroke," said Donald C. Lo, Ph.D., director of the Center for Drug Discovery and associate professor of neurobiology at Duke, and primary investigator on the study

 
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