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Persistent Pulmonary Hypertension News

SSRI Antidepressants Increase Risk of Neonatal PPH

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At a glance:

Persistent Pulmonary Hypertension is a disease in newborns which causes oxygen deprivation and can lead to brain damage, other conditions, and even death.
 
The risk of this condition is increased by the use of SSRI antidepressants by the mother in the second half of pregnancy, leading to a difficult choice for pregnant women with depression.
 
The choice is not clear-cut because a relapse of depression can lead to severe consequences, even suicide, or psychosis leading to harm to the infant after birth.
 
Patients and their doctors must carefully weigh their options.
 

Some widely-used drugs increase risks for baby

Consumer Reports - 3/16/2006 10:14 PM

Three recent research reports create a serious dilemma for pregnant women who take the most commonly prescribed antidepressants. If they stop, they risk a potentially dangerous relapse. But if they continue, the drugs may endanger their newborn's health or even life. The new findings mean that women must work with their doctors to judge which is the lesser of two evils: worsening depression or increased risk to their baby's health.
 
All three studies focused on selective serotonin-reuptake inhibitors (SSRIs), the popular class of antidepressants that includes citalopram (generic, Celexa), fluoxetine (generic, Prozac), paroxetine (generic, Paxil), sertraline (Zoloft), and the closely related drug venlaf
 
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