Parkinson’s Drug Linked to Heart Valve Damage
ISLAMABAD: Heart valve disease appears to be relatively common in Parkinson’s disease patients treated with pergolide (Permax), according to results of a new study. Evidence suggests that the degree of damage correlates with lifetime dose of the drug, but the effects may be reversible.
Pergolide belongs to a class of drugs called dopamine agonists. It is derived from ergot, a substance obtained from plants, and works by acting in place of dopamine, a natural substance in the brain needed to control movement.
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