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Osteonecrosis of the Jaw (ONJ) News

Zometa Helps Breast Cancer Patients Avoid Fractures

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At a glance:

Postmenopausal women with certain types of breast cancer are treated in the long term with the drug Femara to reduce the risk of recurrence; however this treatment carries with it a risk of bone loss.
 
Studies underway suggest that women given injections of Zometa from the onset of their cancer therapy have increased bone mineral density compared with women who did not receive Zometa, thereby reducing risk of fracture.
 
One potential side effect of Zometa treatment is osteoporosis of the jaw, a painful condition of bone loss in the jaw; however the association has yet to be proven.

New Data Show Zometa Increased Bone Mineral Density in Breast

PharmaLive.com (press release) - 3/22/2006 4:56 PM

Studies investigating the effect of hormone therapy in the adjuvant treatment of early breast cancer are ongoing and several studies have shown that women receiving long-term treatment with these drugs are at risk of bone loss. Based on the demonstrated effectiveness of aromatase inhibitors, these medicines are increasingly being used as an integral part of the post-surgery treatment protocol for postmenopausal women with hormone sensitive early breast cancer. Femara, in particular, is being used for its proven ability to reduce the risk that breast cancer will come back. Femara is used in both initial adjuvant and extended adjuvant therapy for breast
 
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