Heart Attacks:

Cox-2 Inhibitors like Vioxx and many hormone replacement therapy drugs have been linked to medication related heart attacks. If you have been hurt by a defective drug like Vioxx or Premarin, read on.

Causes of Heart Attacks and Medications of Ill Repute

Heart attacks are one of the primary causes of death in America. Because of the prevalence of high cholesterol, heart disease and other cardiac conditions, more than one million people in the U.S. suffer heart attacks each year. A heart attack, or myocardial infarction, is the sudden cessation of the blood supply to part of the heart muscle, the myocardium, which is severely occluded or blocked. The blockage typically occurs over a long period of time and is typically a symptom of high cholesterol that develops into arthrosclerosis or hardening of the arteries. Additionally, the coronary arteries that provide the heart with blood and oxygen supply can be compromised by disease if they become narrow and blood cannot flow sufficiently. Fats or plaque builds up; hardening the heart and ultimately something may burst, rupture or rip which will cause a blood clot that ultimately provokes the heart attack.
 
The heart and brain need a consistent supply of blood and oxygen to maintain function and if you suffer from a heart attack and your blood supply is stopped for more than a few minutes, your heart muscle cells can suffer permanent damage. If your heart is damaged too badly, a heart attack sufferer can be disabled or die. Heart attack symptoms can include a feeling of acute discomfort that radiates to the back, the jaw, the throat or the upper arm, a choking feeling, sweating, nausea and vomiting, extreme weakness and dizziness, anxiety or shortness of breath, and chest pressure or heaviness and distinct pain in the chest.
 
Several drugs on today’s market, some of which were recently recalled actually prompted heart attacks in a vast number of people causing pain, injury and many deaths. Some of these prescription drugs include Cox 2 Inhibitors like Bextra, Celebrex and Vioxx and HRT (Hormone Replacement Therapy) drugs like Premarin, Premphase and Prempro.
 
In 2004, Merck, the pharmaceutical giant who developed the Cox 2 Inhibitor Vioxx, was ultimately forced to pull the drug from the market because of the high rate of incidence of heart attacks in patients taking the drug. In one study (out of many published) more than 27,000 sudden cardiac deaths and heart attacks were linked to Vioxx. The FDA did warn patients, prior to the drug being removed from the market, that taking Vioxx created a 50 % higher incidence of heart attacks.
 
Several years ago, it was thought that hormone replacement therapy was the salvation from peri-menopausal and menopausal women across the country. Unfortunately, it was then discovered that many of these hormone replacement therapy drugs were tied to an increased risk of heart attack. Premarin, one of these HRT drugs, was linked to a high incidence of heart disease and heart attacks in women as well as other serious diseases like ovarian cancer, lupus, scleroderma, gallbladder cancer and stroke.
 
If you or someone you love has been the victim of a heart attack because of exposure to a defective drug or defective product, you should consult with a personal injury attorney or with a product liability attorney as soon as you can.

 

Informative Articles About Heart Attacks

· Understanding the Risks and Alternative Uses of Cox-2 Inhibitors / Arthritis Medications

  4/18/2006 6:00:00 AM | Cox 2 Hazards and Alternative Arthritis Medications

· Vioxx Side Effects and Merck's Knowledge

  4/13/2006 9:15:00 AM | Vioxx Recall and Side Effects History

 Latest Heart Attacks & Related Newswire

· More Damaging Vioxx Evidence in Trial - San Jose Mercury News

  7/5/2006 9:30:00 PM | Witness says studies showed Vioxx users at risk of heart ailments
  Comments:(0)
   More compelling testimony for the plaintiffs in the California Vioxx trial: Dr. Lemuel Moye of the University of Texas said his analysis of early Vioxx trials concluded that the risks of heart attack and stroke outweighed the benefits.  Further, some trials excluded patients who were at a higher risk of heart attack, thus skewing the resu...
     Read More

· Ken Lay's Death of Medical Interest - MedPage Today

  7/5/2006 5:26:00 PM | Lay's Death Viewed as Cautionary Tale of Catastrophic Stress
  Comments:(0)
   From a medical point of view, Ken Lay's death, if confirmed to be due to heart disease, was not surprising. Uncontrollable, devastating life events are known to be risk factors for sudden cardiac death. They can bring on ventricular fibrillation followed by cardiac arrest, or cause an artery to close up or plaque (chunk of cholesterol) to brea...
     Read More

· California Vioxx Trial Hears More Testimony About Clinical Studies - North County Times

  6/30/2006 3:12:00 PM | Merck Scientist Testifies Vioxx Caused More Heart Attacks Than ...
  Comments:(0)
   Jurors for the California Vioxx trial continued to view videotaped depositions on the third day of the trial. A Merck researcher, Dr. Deborah Shapiro, testified that a 1999 study of 8000 patients showed that those given Vioxx had four times the number of heart attacks than those given Aleve (naproxen), an older NSAID. Merck claims that there i...
     Read More

· Testimony Begins in California Vioxx Trial: Merck Did Not Submit Test Results to FDA - San Jose Mercury News

  6/29/2006 3:04:00 AM | Testimony: Feds not told about tests that exposed Vioxx dangers
  Comments:(0)
   The former head of Merck's research laboratories was heard in a video deposition on the second day of the Vioxx trial in California. Dr. Edward Scolnick said that two studies in 2001 showed that patients on Vioxx were 2-4 times more likely to die than patients on placebo; however Merck did not submit these results to the FDA. Merck is being su...
     Read More

· Opening Statements in California Vioxx Trial - NorthJersey.com

  6/28/2006 9:13:00 AM | Plaintiff says Merck knew of potential dangers with Vioxx
  Comments:(0)
   The first Vioxx trial to be held in California is under way.  In opening statements, the plaintiff's lawyer said that Merck was aware of Vioxx's risks as far back as 1996 and did not inform doctors. Furthermore, the company specifically trained salespeople to downplay the risks. Stewart Grossberg claims the drug caused his heart attack an...
     Read More


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